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Applied Biosystems

Biochips - A Global Update Of Market Trends & Opportunities

The biochip industry is in the early stages of growth and hence, not only promises potential but also is susceptible to vagaries of market forces. Competition, patent disputes, knowledge constraints (in terms of skilled employees, technical know-how) and financial strength might be a few impediments for firms engaged in this industry. A promising market arises from three factors – an aging population, third party reimbursement and a growing number of individuals suffering from common chronic diseases. Biochips would certainly evolve in terms of physical, technical characteristics, and with focus on miniaturization of assays, they would turn smaller and more powerful with each generation. The industry is characterized by both intense rivalry and equally well-developed web of alliances.

These and other market data and trends are presented in “Biochips: A Global Update of Market Trends & Opportunities” by BizAcumen, Inc. Our reports are designed to be most comprehensive in geographic coverage and vertical market analyses.

Biotechnology Industry: Biochips - A Global Update of Market Trends & Opportunities
Company Profile, SWOT and Revenue Analysis!

1. METHODOLOGY 1
Study Reliability and Reporting Limitations 1
Disclaimers 2
Quantitative Techniques & Reporting Level 3

2. INDUSTRY OVERVIEW 4
Promising Biochips Promote Biological Research 4
Market Scenario across Products and Regions 4
DNA Chips Lead the Application Front 5
Probable Industry Directions 5
Biochip Technology Boosts Personalised Medicine 6
Biochip Technology Spreads beyond Pharma Industry 7
Protein Chips to Shape the Future 7
Proteomics “Chip” into Biochip Technology 8
Towards Increasing Minaturization 8
European Advancements Set Diagnostic Procedures 8
Competitive Scenario 8
Major Participants 8
Roche and Affymetrix Taste Success in the Diagnostics Market 10
Growing Partnerships between Pharma and Biotech Companies 10
Tech Giants Join the Biochip Fray 11

3. PRODUCT FACTS 12
A. DNA Chips 12
B. Protein Chips 13
C. Lab Chips 13

4. APPLICATIONS OF BIOCHIPS 13
Biochip Uses 14
Biochips and Pharmaceutical Investigation 14
Biochips and Medical Diagnostics 15
Advantages of Biosensor Chip Technology 15
Biochips and Forensics 16
Biochips and Transplantation Screening 16
Biochips and Identity Testing 16
Biochips and Water and Environmental Testing 16
Food Industry 16

5. TRENDS 17
Industry Characteristics 17
New Products and Players to Drive Market 17
Key Forces Boosting the Industry 17
Industry Structure 17
Industry Challenges 18
Price Dearness Pauses Biochips Growth 18
Current Approaches to Biochips 19
The Business of Biochips 19
Technological Trends 20
Sensitivity 20
Microfabrication 20
Density 20
Integrated Chips 21
Patent Trends 21
Patent Applications 21

6. NEXT GENERATION TECHNOLOGY 22
Microfluidics Using CD-ROM Technology 22

7. CORPORATE DEVELOPMENTS 23
Affymetrix Acquires USB 23
Illumina Announces Partnership with Genpathway for ChIP
Sequencing Services 23
Affymetrix and Avesthagen Enter into an Agreement 24
Roche NimbleGen and Affymetrix Announce Expansion of License
Agreement 24
GATC Biotech Establishes New Subsidiary 25
Affymetrix Introduces Complete Cytogenetic Solution 25
Sigma Launches ChIP Kit 25
US and Czech Scientists to Develop Biochips for Detecting Cancer 26
Roche Takes Over NimbleGen 26
GenTel BioSciences Acquires Protein Chip Platform Assets of GSK 27
Advanced Liquid Logic Acquires Nanolytics 27
Applied Microarrays Acquires Select GE Healthcare’s Assets 27
Affymetrix and Partners Healthcare Extend Collaboration 28
Agencourt, NuGEN and Affymetrix Clinical Services Collaborate 29
Affymetrix Inks Licensing Agreement with Empire Genomics 29
Caliper Enters into a Licensing Agreement with Monogram
Biosciences 30
Affymetrix and IPSOGEN Sign Agreement 30
bioMérieux and NuGEN Enter into Supply and Cross-License
Agreement 31
VWR and CapitalBio Enter into a Distribution Agreement 31
UCL Subsidiary and Roche Diagnostics Ink Licensing Deal 32
Affymetrix Establishes the European Cytogenetic Research
Initiative. 32
Roche Introduces Gene Expression Services and Arrays 32
Affymetrix Unveils Affymetrix GeneChip Command Console Software 33
Affymetrix Introduces GeneChip Mouse and Rat Gene 1.0 ST Arrays 33
Affymetrix Unveils Genome-Wide Human SNP Array 6.0 34
Caliper Life Sciences Launches High Throughput RNA Assay 35
Applied Biosystems Unveils DNA Tools 35
febit Launches Geniom RT Analyzer 35
Austrian Research Center Develops New Biochip Surface 36
Researchers Develop Biochips to Eliminate Animal Testing 36

8. MAJOR PLAYERS 37
Affymetrix (US) 37
Applied Biosystems Group (US) 37
Biomerieux (France) 37
Bio-Rad Laboratories, Inc. (US) 37
Caliper Life Sciences, Inc. (US) 37
Cepheid Inc. (US) 38
GE Healthcare Ltd (UK) 38
Takara Bio, Inc. (Japan) 38
Zyomyx (US) 38

9. MARKET ANALYTICS 39

10. THE UNITED STATES 43
Biochips Market Overview 43
Time Saving Biochips - All Set to Grow 43
Multiple Applications of Biochips Drive Sales 43
Biochip Market Faces Challenges 43

11. CANADA 45

12. JAPAN 46
DNA Chip Based on Printing Technology 46
DNA Chips to Reveal Links Among Genes 47
A Leading Japanese Biochip Player - Takara Shuzo 47
ICAN ™ Technology for Large-Scale Production of DNA Fragments 48

13. EUROPE 50

a. France 52

b. Germany 53

c. The United Kingdom 55

d. Rest of Europe 56

14. REST OF WORLD 57
China 58
Basic Environment and Commercial Development 58
Biochip Research 58
Status of Biochip Industry in China 59
Taiwan 59
Taiwan Pursues Promise of Biochip Sector 59
International Advantage Sought 60

EXHIBITS

Table 1: Market Shares of Biochips Patent Applications in the
World - 2003

Table 2: Global Biochips Market by Region for the Period
2007-2015 (Sales in US$ Million)

Table 3: Percentage Breakdown of Global Biochips Market by
Region for the Years 2008 & 2012

Table 4: Global DNA Chips Market by Region for the Period
2007-2015 (Sales in US$ Million)

Table 5: Percentage Breakdown of Global DNA Chips Market by
Region for the Years 2008 & 2012

Table 6: Global Protein Chips Market by Region for the Period
2007-2015 (Sales in US$ Million)

Table 7: Percentage Breakdown of Global Protein Chips Market
by Region for the Years 2008 & 2012

Table 8: Global Lab Chips Market by Region for the Period
2007-2015 (Sales in US$ Million)

Table 9: Percentage Breakdown of Global Lab Chips Market by
Region for the Years 2008 & 2012

Table 10: Biochips Market by Segment in the US: 2007-2015
(Sales in US$ Million)

Table 11: Percentage Breakdown of Biochips Market by Segment
in the US for the Years 2008 & 2012

Table 12: Biochips Market by Segment in Canada: 2007-2015
(Sales in US$ Million)

Table 13: Percentage Breakdown of Biochips Market by Segment
in Canada for the Years 2008 & 2012

Table 14: Biochips Market by Segment in Japan: 2007-2015
(Sales in US$ Million)

Table 15: Percentage Breakdown of Biochips Market by Segment
in Japan for the Years 2008 & 2012

Table 16: Biochips Market by Region in Europe: 2007-2015
(Sales in US$ Million)

Table 17: Percentage Breakdown of Biochips Market by Region in
Europe for the Years 2008 & 2012

Table 18: Biochips Market by Segment in Europe: 2007-2015
(Sales in US$ Million)

Table 19: Percentage Breakdown of Biochips Market by Segment
in Europe for the Years 2008 & 2012

Table 20: Biochips Market by Segment in France: 2007-2015
(Sales in US$ Million)

Table 21: Percentage Breakdown of Biochips Market by Segment
in France for the Years 2008 & 2012

Table 22: Biochips Market by Segment in Germany: 2007-2015
(Sales in US$ Million)

Table 23: Percentage Breakdown of Biochips Market by Segment
in Germany for the Years 2008 & 2012

Table 24: Biochips Market by Segment in the UK: 2007-2015
(Sales in US$ Million)

Table 25: Percentage Breakdown of Biochips Market by Segment
in the UK for the Years 2008 & 2012

Table 26: Biochips Market by Segment in Rest of Europe:
2007-2015 (Sales in US$ Million)

Table 27: Percentage Breakdown of Biochips Market by Segment
in Rest of Europe for the Years 2008 & 2012

Table 28: Biochips Market by Segment in Rest of World:
2007-2015 (Sales in US$ Million)

Table 29: Percentage Breakdown of Biochips Market by Segment
in Rest of World for the Years 2008 & 2012

About the Author

Roger Miller

Market Research Report

Applied Biosystems $70.1 Applied Biosystems, Inc. (formerly NASDAQ: ABIO) is the original name of a pioneer biotechnology company founded in 1981 in Foster City, California, in the San Francisco Bay Area. Through the 1980s it operated independently and manufactured biochemicals and automated genetic engineering and diagnostic research instruments, including the principal brand of DNA sequencing machine used by the Human Genome Project consortium centers. Applied Biosystems close ties to the consortium project led to the idea for the founding of Celera Genomics (NYSE: CRA) in 1998 as one of several independent competitors to the consortium. In 1993 Applied Biosystems was delisted from the NASDAQ when it was acquired by the old company known then as PerkinElmer (formerly NYSE: PKN). Author: Miller, Frederic P./ Vandome, Agnes F./ McBrewster, John Binding Type: Paperback Number of Pages: 88 Publication Date: 2010/07/25 Language: English Dimensions: 5.98 x 9.01 x 0.21 inches

Mathematical Methods Applied to Biosystems $100.37 A lot of new applications of main disciplines such as physics, mathematics, and engineering to the study of biological systems arise at an impressive rate. The mathematicallyoriented research of biosystems can lead to useful ways of understanding and transforming many naturallyocurring mechanisms in such systems. This book provides two different mathematical approaches for studying some processes at the intracellular and cell membrane level, as well as their application to other interesting problems in physics. The first part deals with factorization and supersymmetric methods, developed in the context of mathematicalphysics, as applied to the polymerization of tubulin dimers and the motion of domain walls in microtubules, which are one of the basic components of cell skeleton. The second part deals with the control of neuronal dynamics through synchronization in a minimal ensemble of two HodgkinHuxley neurons by using the nonlinear control theory. These methods may be especially useful to proffesionals in the fields of physics, mathematics, control theory, biology, and to anyone else who may be interested in interdisciplinary scientific investigations. Author: CornejoPerez, Octavio/ C. Rosu, Haret/ Femat, Ricardo Binding Type: Paperback Number of Pages: 116 Publication Date: 2010/09/14 Language: English Dimensions: 6.00 x 9.02 x 0.28 inches

Mathematical Modelling of Biosystems $239.98 This volume is an interdisciplinary book which introduces, in a very readable way, stateoftheart research in the fundamental topics of mathematical modelling of Biosystems. In short, the book offers an overview of mathematical and computational modelling of biosystems including biological phenomena in general. There is also a special introduction to Protein Physics which aims to explain the allornone first order phase transitions from native to denatured states. Author: Mondaini, Rubem P./ Pardalos, Panos M. Series Title: Applied Optimization Series Number: 102 Binding Type: Paperback Number of Pages: 317 Publication Date: 2010/11/19 Language: English Dimensions: 9.21 x 6.14 x 0.67 inches

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Biosystems Engineering $127.5 No Synopsis Available

Modelling, Analysis and Optimization of Biosystems $221.44 In general, several mathematical models can be designed in order to describe a biological or medical process and there is no unique criterion which model gives the best description. This book presents several of these models and shows applications of them to different biological and medical problems. The book shows that operations research expertise is necessary in respect to modeling, analysis and optimization of biosystems. Author: Krabs, Werner/ Pickl, Stefan Binding Type: Paperback Number of Pages: 203 Publication Date: 2010/11/10 Language: English Dimensions: 9.21 x 6.14 x 0.46 inches

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Immobilized Biosystems: Theory and Practical Applications $389.03 No Synopsis Available

Quantitative Understanding of Biosystems: An Introduction to Biophysics $87.7 No Synopsis Available

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A Biosystems Approach to Industrial Patient Monitoring and Diagnostic Devices $52 No Synopsis Available

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